CGM continuity (Dexcom)
Continuous glucose capture with monitoring for gaps, uploads, and protocol-defined windows—so outcomes remain interpretable.
Diabetes, Obesity & GLP-1 Programs
Metabolic endpoints fail quietly. Delve prevents that.
Missed CGM uploads. Weigh-ins that don’t happen. Adherence drift between visits. Delve combines Dexcom CGM, Withings digital weight capture, and activity wearables with a real-time compliance operating model and concierge follow-through—so you get usable endpoints, not just collected data.
Type 2 Diabetes
Obesity / Weight Management
GLP-1 / Incretin Therapies
Cardiometabolic Risk
NAFLD / NASH (as scoped)
Hypertension (as scoped)
Pre-diabetes
Real-World Evidence
CGM capture
Dexcom
Continuity monitoring + rescue
Weight capture
Withings
Routine reinforcement + evidence trail
Adherence ops
Owned
Concierge + live oversight
Built for metabolic realities
More than data capture—an operational model that protects the endpoint.
In metabolic programs, the endpoint integrity depends on consistent daily capture: CGM continuity, weigh-in routines, and activity adherence. Delve monitors signal health, rescues adherence drift, and documents interventions—before missingness becomes the headline.
Digital weight capture (Withings)
Remote weigh-ins with routine reinforcement, alerting, and evidence trails—reducing site follow-up burden.
Activity + behavior context
Wearables provide activity/sleep context for weight and glucose patterns—captured continuously, QC’d, and export-ready.
Why Delve
Metabolic trials are not “visit-managed.” They are behavior-managed.
Diabetes, obesity, and GLP-1 endpoints degrade through day-to-day friction: CGM gaps, skipped weigh-ins, scale issues, app fatigue, and routine breakdowns. Delve closes these gaps by owning adherence operations and device telemetry—continuously, not retrospectively.
Traditional CRO
Strong at visits and monitoring cadence
- Site oversight and monitoring plans
- Visit management and reporting structure
- Issues escalated after trends are noticed
- Limited ownership between visits
Risk: CGM and weigh-in drift accumulates quietly; missingness becomes irreversible inside protocol windows.
CRO + point tools
More tools, more accountability gaps
- Separate vendors for CGM, scales, wearables, ePRO, reminders, logistics
- Disconnected streams and unclear ownership of follow-up
- Sites absorb troubleshooting and patient outreach
- QC happens after weeks of drift
Risk: the dataset locks with preventable gaps and post-hoc cleaning becomes the workflow.
Delve delivery model
Owned compliance + owned telemetry
- Live CGM continuity, weigh-in routines, and device-health visibility
- Concierge team intervenes when drift appears
- Protocol-driven alerts and escalation pathways
- Evidence trails: what happened, actions taken, outcome
Outcome: higher usable data yield, fewer deviations, lower site burden, stronger retention.
Metabolic Evidence Chain
CGM + weight + activity + interventions = usable endpoints.
Metabolic endpoints are sensitive to missingness and adherence. Delve closes the loop with telemetry, quality gates, and documented interventions when the chain breaks.
CGM: continuity, gaps, upload success, protocol windows and rescue
Weight: remote weigh-ins, routine reinforcement, device health and troubleshooting
Interventions: concierge outreach, coaching, replacements, escalation to sites
How We Engage
Flexible models—from prime execution to CRO integration.
Full-Service Metabolic Delivery (Prime)
Delve leads execution end-to-end with a metabolic operating model built around continuous capture, adherence rescue, and protocol-defined interventions. Specialty functions can be delivered directly or through Delve-led partners as scoped.
- Start-up + site coordination
- Dexcom CGM + Withings weight + activity wearables
- Real-time QC + compliance + retention ownership
Hybrid With Your CRO
Keep your CRO for monitoring/EDC and plug Delve in as the digital capture + adherence operations layer. We reduce missingness, improve device adherence, and provide live risk visibility.
- Delve owns telemetry, compliance ops, and concierge support
- Protocol-driven alerts + escalation pathways
- Cleaner datasets at lock with fewer late-cycle fixes
Site Network Enablement
We offload the most time-consuming follow-up work—device troubleshooting, weigh-in outreach, reminders, and re-training—so sites can focus on enrollment and clinical oversight.
- Coordinator relief: onboarding, reminders, rescheduling
- Device replacements and patient coaching
- Study-wide oversight dashboards for networks
Live Metrics (Example)
What sponsors and study teams see in Delve.
These are example visuals to demonstrate how we monitor CGM continuity, weigh-in adherence, and wearable sync in real time. Your study’s dashboards reflect your protocol, schedules, and site structure.
CGM continuity with interventions
Markers indicate documented interventions (coaching, troubleshooting, replacements) that prevent gaps.
Weigh-in adherence (Withings)
Routine reinforcement and escalation reduce missed weigh-ins and support retention.
Wearable sync health
Telemetry surfaces connectivity issues early so the team can recover data within protocol windows.
Protocol-to-Analysis
End-to-end metabolic delivery—mapped to real failure points.
“End-to-end” means ownership with evidence trails—from protocol operationalization and device plans through compliance rescue, data QC, and analysis readiness.
Step 1
Protocol operationalization
- SOA converted into executable tasks and visit windows
- Risk register: CGM gaps, weigh-in adherence, device friction
- Intervention rules + escalation pathways defined
Step 2
Device + endpoint mapping
- Dexcom capture plan aligned to endpoint intent
- Withings weigh-in routines and handling rules
- Telemetry plan: wear-time, sync, battery, QC flags
Step 3
Feasibility + site enablement
- Site/network strategy aligned to burden
- Start-up coordination and readiness tracking
- Training workflows for coordinators and investigators
Step 4
Onboarding + routines
- Patient training: CGM, weigh-ins, wearables, ePRO
- Routines and reminders aligned to protocol windows
- Multilingual concierge support for ongoing questions
Step 5
Conduct: adherence operations
- Real-time monitoring: CGM gaps, weigh-ins, wearable sync
- Concierge outreach when compliance drifts
- Documented interventions + outcomes (audit-ready)
Step 6
Tolerability + AE context
- ePRO for symptoms and tolerability (e.g., GI, fatigue)
- Protocol-driven triggers and routing to sites
- Evidence trails of follow-up actions and closure
Step 7
Data quality + reconciliation
- QC checks, missingness surveillance, and flags
- Reconciliation across CGM, weight, ePRO, and exports (as scoped)
- Site/network performance monitoring and retraining needs
Step 8
Analysis readiness + close-out
- Analysis-ready exports and documented handling rules
- Close-out package: adherence summary + QC outcomes
- Support for interim looks and endpoint review (as scoped)
Metabolic Capabilities
Execution built for daily routines—not just clinic visits.
Dexcom CGM capture you can operationalize
Metabolic endpoints require continuity. We monitor capture, gaps, and adherence so glucose data is usable.
- CGM continuity monitoring and gap detection
- Protocol-driven alerts and rescue workflows
- Audit-ready logs tied to interventions
Withings weight capture that actually happens
Weight change is only meaningful if weigh-ins are consistent. We build and enforce the routine.
- Remote weigh-in routines and reminders
- Troubleshooting, retraining, replacements as needed
- Site-friendly escalation pathways
Activity wearables for behavior context
Activity and sleep explain variance in glucose and weight. We collect, QC, and reconcile these streams.
- Wear-time estimation + device-health telemetry
- Activity/sleep context layered into oversight
- Exports aligned to your analysis plan (as scoped)
Deliverables
What you receive when Delve runs metabolic execution.
- Operational study plan + metabolic execution risk register
- Dexcom CGM capture plan + continuity monitoring workflows
- Withings weight plan: routines, reminders, troubleshooting scripts
- Wearables plan: provisioning, telemetry monitoring, replacement SOP
- Data quality plan: QC checks, missingness rules, reconciliation approach
- Weekly risk report: adherence, retention, device health, site performance
- Close-out evidence package: intervention logs, adherence summary, QC outcomes
From daily behavior to analysis-ready evidence
Metabolic trials don’t fail because the endpoint is unclear. They fail because the routine breaks. Delve operationalizes CGM continuity, weigh-in adherence, and wearable capture—then documents interventions—so your datasets are usable.
- Continuous telemetry and missingness surveillance across CGM, weight, and activity
- Documented interventions (what happened, when, why, outcome)
- Reconciliation across digital sources and exports (as scoped)
- Readiness support for interim looks and endpoint performance reviews (as scoped)
If you already have DM/biostats partners, Delve strengthens the operational evidence chain without replacing your stack.
Planning a diabetes, obesity, or GLP-1 study?
If your endpoints depend on consistent daily capture—CGM continuity, remote weigh-ins, activity context—Delve is built to protect that evidence chain. We can lead end-to-end execution or integrate with your CRO to improve compliance, retention, and usable data yield.