Photo QC & re-capture loops
Quality gates for lighting, framing, and consistency—plus re-capture prompts before unusable images spread.
Dermatology Trials
Make derm endpoints usable before the visit.
Delve runs the between-visit operating model: topical routines, symptom capture, and standardized photography—backed by concierge follow-through and live oversight—so missingness gets resolved early, not explained later.
Dermatology studies live and die between visits: topical adherence, flare timing, itch and pain capture, standardized photography, and consistent assessment routines. Delve combines CRO-style execution with a real-time compliance operating model—eCOA/ePRO, photo workflows, concierge follow-through, kit logistics, and live oversight— so you get usable evidence, not just collected data.
Atopic Dermatitis
Psoriasis
Hidradenitis Suppurativa
Acne
Vitiligo
Alopecia
Between-visit adherence
Owned
Topicals, diaries, photo cadence
Data quality
Live
Photo QC + missingness alerts
Site burden
Lower
Concierge absorbs follow-up load
Explore Delve by therapeutic area
Built as a connected execution model.
Dermatology is one view of the same operating system: compliance ownership, reduced site burden, and real-time intervention. Explore other therapeutic areas — and the post-market hub that ties them together.
Oncology
High-burden protocols where between-visit symptom capture and retention decide data integrity.
Explore oncology execution →
Rare Disease
Small cohorts where every missed day matters — caregiver workflows, logistics, and adherence rescue.
Explore rare disease execution →
Diabetes / Obesity
CGM + weight + long follow-up where device fatigue and silent dropout must be detected early.
Explore metabolic execution →
CNS
Fatigue-sensitive tasks and wear-time risk — adherence operations matters more than dashboards.
Explore CNS execution →
Post-Market & Long-Term Studies
The operating model for 3–5 year follow-up: detect drift early, intervene fast, and keep endpoints usable.
Go to post-market hub →
Cardiology
Long-term physiological monitoring where wear-time decay, silent data loss, and delayed escalation threaten endpoint integrity.
Explore cardiology execution →
Designed for dermatology realities
More than a platform—an operational model that protects the endpoint.
Dermatology success depends on consistency between visits. Delve enforces imaging standards, supports adherence routines, and rescues missingness before it becomes a protocol deviation.
Between-visit adherence operations
Topical routines, diaries, and symptom capture reinforced by reminders and human follow-through.
Lower site burden
Concierge handles participant training, troubleshooting, and rescheduling—so coordinators can focus on assessments.
Why Delve
Derm trials are not “visit-managed.” They are behavior-managed.
In dermatology, the evidence chain breaks through routine friction: topicals are skipped, photos are inconsistent, symptoms go unreported, and flare timing is missed. Delve closes these gaps by owning adherence operations and documenting interventions—continuously, not retrospectively.
Traditional CRO
Strong at visit cadence
- Monitoring and reporting structure
- Site communication and oversight
- Standardized processes and templates
- Issue escalation after findings emerge
Risk: derm adherence and photo quality degrade between visits; issues are discovered late and fixed expensively.
CRO + point tools
More tools, more failure points
- Separate vendors for ePRO, imaging, reminders, logistics
- Disconnected data streams and unclear accountability
- Sites absorb follow-up, re-training, re-capture
- Data QC happens after weeks of drift
Risk: “missingness” becomes the story, not the endpoint.
Delve delivery model
Owned compliance + owned photo quality
- Real-time adherence visibility (topicals, diaries, photos)
- Concierge team intervenes when drift appears
- Photo QC rules + re-capture loops before visits
- Evidence trails: what happened, actions taken, outcome
Outcome: higher usable data yield, fewer protocol deviations, lower site burden, stronger retention.
Dermatology Evidence Chain
Standardized imaging + symptoms + interventions = usable endpoints.
Dermatology endpoints are especially sensitive to between-visit variability. Delve closes the loop with quality gates, real-time alerts, and documented interventions when the chain breaks.
Photo QC: lighting, framing, angle, consistency, re-capture triggers
Symptom capture: itch/pain/sleep, flare timing, treatment burden
Interventions: concierge coaching, rescheduling, re-training, escalation pathways
How We Engage
Flexible models—from prime execution to CRO integration.
Full-Service Dermatology Delivery (Prime)
Delve leads execution end-to-end with a derm operating model built around adherence, imaging quality, and real-time oversight. Specialty functions can be delivered directly or through Delve-led partners as scoped.
- Start-up + site coordination
- Patient operations + concierge follow-through
- eCOA/photo/logistics + live quality control
Hybrid With Your CRO
Keep your CRO for monitoring/EDC and plug Delve in as the compliance, imaging, and participant operations layer. We reduce missingness, improve photo consistency, and provide live risk visibility.
- Delve owns adherence operations and patient support
- Photo QC + re-capture + escalation pathways
- Cleaner datasets at lock with fewer late-cycle fixes
Site Network Enablement
We offload the most time-consuming derm follow-up work—topical reminders, diary completion, photo coaching, and re-capture—so sites can focus on assessments and enrollment.
- Coordinator relief: reminders, training, rescheduling
- Patient coaching for consistent at-home photos
- Study-wide oversight dashboards for networks
Live Metrics (Example)
What sponsors and study teams see in Delve.
These are example visuals to demonstrate how we monitor adherence, imaging quality, and completion trends in real time. Your study’s dashboards reflect your protocol, schedules, and site structure.
Adherence trend with interventions
Markers indicate documented interventions (coaching, re-training, rescheduling) that prevent drift.
Photo QC pass rate
Quality gates surface low-confidence images early, enabling re-capture within protocol windows.
Task completion by site
Sites with higher friction get proactive concierge support and targeted retraining workflows.
Protocol-to-Analysis
End-to-end dermatology delivery—mapped to real failure points.
“End-to-end” means ownership with evidence trails—from protocol operationalization and imaging standards through compliance rescue, data QC, and analysis readiness.
Step 1
Protocol operationalization
- SOA converted into executable tasks and visit windows
- Derm risk register: adherence, imaging, flare timing
- Intervention rules + escalation pathways defined
Step 2
Imaging & assessment standards
- Photo capture SOPs and participant coaching plan
- Quality gates: lighting, framing, reference markers
- Re-capture workflows before endpoint drift spreads
Step 3
Feasibility + site enablement
- Site/network strategy aligned to indication and burden
- Start-up coordination and readiness tracking
- Training workflows for coordinators and investigators
Step 4
Onboarding + compliance setup
- Topical routines, diary schedules, and reminders configured
- Patient training: photos, symptom capture, supplies
- Multilingual concierge support for ongoing questions
Step 5
Conduct: adherence operations
- Real-time task adherence monitoring (topicals/diaries/photos)
- Concierge outreach when compliance drifts
- Documented interventions + outcomes (audit-ready)
Step 6
Safety & symptom escalation
- Protocol-driven triggers for worsening symptoms/AE signals
- Structured routing to site/sponsor teams
- Evidence trails of follow-up actions and closure
Step 7
Data quality + reconciliation
- Missingness surveillance across ePRO and imaging
- Photo QC exceptions tracked and resolved
- Reconciliation across sources and exports (as scoped)
Step 8
Analysis readiness + close-out
- Analysis-ready exports and documented handling rules
- Close-out package: adherence summary + QC outcomes
- Support for interim looks and endpoint performance review (as scoped)
Dermatology Capabilities
Execution built for dermatology realities.
Topical adherence is the endpoint risk
Derm efficacy signals are sensitive to dosing routines, washout rules, and daily behavior—not just site visits.
- Protocol-driven dosing diaries and reminders
- Human follow-through when adherence drifts
- Documented deviations + rescue actions with timestamps
Imaging workflows that prevent unusable photos
Low-quality at-home photos silently corrupt endpoints. We enforce capture standards before data is lost.
- Guided capture instructions + coaching scripts
- Quality gates (lighting, distance, angle, framing)
- Re-capture loops and escalation to sites when needed
Symptom capture that matches flare reality
Itch, pain, sleep disruption, and flare timing need consistent capture—without adding workload to sites.
- ePRO schedules for itch, pain, sleep, QoL, flare events
- Concierge outreach for missed entries and confusion
- Site relief: fewer calls, fewer late diary reconciliations
Deliverables
What you receive when Delve runs dermatology execution.
- Operational study plan + dermatology execution risk register
- Participant adherence plan: topicals/diaries/photo cadence + scripts
- Imaging SOP: capture standards, QC rules, re-capture workflow
- Data quality plan: missingness rules, QC checks, reconciliation approach
- Weekly risk report: adherence, retention, imaging quality, site/network performance
- Close-out evidence package: intervention logs, adherence summary, QC outcomes
From patient behavior to analysis-ready evidence
Derm studies don’t fail because the endpoint is unclear. They fail because the routine breaks. Delve operationalizes adherence, enforces imaging standards, and documents interventions—so your datasets are usable.
- Continuous missingness surveillance across tasks and imaging
- Documented interventions (what happened, when, why, outcome)
- Reconciliation across digital sources and exports (as scoped)
- Readiness support for interim looks and endpoint reviews (as scoped)
If you already have DM/biostats partners, Delve strengthens the operational evidence chain without replacing your stack.
Download
Post-Market Compliance Playbook (Sponsor Edition)
A practical operating model for long-term follow-up: how to detect compliance drift early, intervene fast, reduce site burden, and keep endpoints usable across eCOA + photos + wearables.
What’s inside
- Between-visit compliance ownership model
- Intervention workflows + escalation paths
- Photo QC and re-capture governance
Who it’s for
- Clinical Operations
- Medical Affairs / Post-Approval
- RWE / HEOR teams
Planning a dermatology study?
If your endpoints depend on consistent behavior between visits—topicals, diaries, photos, flare reporting—Delve is built to protect that evidence chain. We can lead end-to-end execution or integrate with your CRO to improve compliance and retention.
FAQ
Dermatology trial compliance: common questions
The failure points that quietly break derm endpoints: photos, symptoms, adherence, and between-visit drift.
How do you standardize at-home dermatology photography?
We enforce capture standards (lighting, framing, distance, angle, reference markers) and use quality gates plus re-capture loops so unusable photos are corrected inside protocol windows—not discovered at the visit or at lock.
Why do derm studies lose compliance between visits?
Derm endpoints depend on daily routines: topical adherence, symptom capture, and photo cadence. Drift starts small and compounds. Without an operating model that intervenes early, missingness becomes normalized.
Does eCOA alone solve derm compliance?
eCOA can capture tasks and generate alerts, but it doesn’t guarantee recovery. Delve pairs real-time monitoring with concierge follow-through to resolve missed entries, confusion, and device friction in hours—not weeks.